Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995242 | 1.00 | GRM5 (0.60) | GRM5ALDH1A1KDM4ECACNA1CSCN5A | |
| SCHEMBL10997158 | 0.93 | GRM5 (0.56) | GRM5ALDH1A1NLRP3TDP1POLB | |
| SCHEMBL10997160 | 0.93 | GRM5 (0.56) | GRM5ALDH1A1NLRP3TDP1POLB | |
| SCHEMBL10993124 | 0.84 | GRM5 (0.62) | GRM5ALDH1A1KDM4ECYP2C19TDP1 | |
| SCHEMBL10993126 | 0.84 | GRM5 (0.62) | GRM5ALDH1A1KDM4ECYP2C19TDP1 | |
| SCHEMBL10989017 | 0.83 | GRM5 (0.68) | GRM5ALDH1A1KDM4ENLRP3CYP3A4 | |
| SCHEMBL10996908 | 0.83 | GRM5 (0.61) | GRM5ALDH1A1KDM4ENLRP3CYP2C19 | |
| SCHEMBL10989034 | 0.83 | GRM5 (0.68) | GRM5ALDH1A1KDM4ENLRP3CYP3A4 | |
| SCHEMBL10996903 | 0.83 | GRM5 (0.61) | GRM5ALDH1A1KDM4ENLRP3CYP2C19 | |
| SCHEMBL10989727 | 0.83 | GRM5 (0.61) | GRM5ALDH1A1KDM4ECYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |