Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 10/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997075 | 0.82 | ALDH1A1 (0.44) | HTTALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL10997559 | 0.69 | MAPT (0.48) | HTTALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL1861019 | 0.68 | MAPT (0.43) | HTTALDH1A1MAPTKDM4ECYP1A2 | |
| Methoxymethane SCHEMBL28044932 | 0.62 | MAPT (0.39) | HTTALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL10216413 | 0.57 | MAPT (0.44) | HTTALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL17070902 | 0.57 | KDM4E (0.51) | HTTALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL141994 | 0.56 | GSK3A (0.44) | HTTPOLBHSD17B10 | |
| SCHEMBL21027734 | 0.56 | MAPT (0.43) | HTTALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL13839599 | 0.52 | ALDH1A1 (0.47) | HTTALDH1A1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL24684881 | 0.51 | ADORA2A (0.44) | HTTCYP1A2L3MBTL1POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158921-A2 | 5-Imino-imidazolidinedione derivatives and process for the preparation of N,N'-disubstituted 5-imino-imidazolidinediones | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |