Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996345 | 0.78 | ALPG (0.42) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL10997907 | 0.71 | KMT2A (0.46) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11000208 | 0.71 | ALPL (0.55) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10997208 | 0.69 | HTT (0.36) | MAPTALDH1A1LMNAHTTHSD17B10 | |
| Azobenzene SCHEMBL182578 | 0.67 | ALDH1A1 (0.92) | MAPTALDH1A1HTTKMT2AMEN1 | |
| Azobenzene SCHEMBL182577 | 0.67 | ALDH1A1 (0.92) | MAPTALDH1A1HTTKMT2AMEN1 | |
| Azobenzene SCHEMBL29154401 | 0.66 | ALDH1A1 (0.67) | MAPTALDH1A1LMNAHTTKMT2A | |
| Azobenzene SCHEMBL9435350 | 0.65 | ALDH1A1 (0.75) | MAPTALDH1A1LMNAHTTKMT2A | |
| Azobenzene SCHEMBL475771 | 0.65 | ALDH1A1 (0.75) | MAPTALDH1A1LMNAHTTKMT2A | |
| Azobenzene SCHEMBL11328908 | 0.65 | ALDH1A1 (0.86) | MAPTALDH1A1LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158921-A2 | 5-Imino-imidazolidinedione derivatives and process for the preparation of N,N'-disubstituted 5-imino-imidazolidinediones | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |