Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.58 |
| ▸ | PPARG | P37231 | 11/20 | 0.58 |
| ▸ | RXRA | P19793 | 5/20 | 0.58 |
| ▸ | RXRB | P28702 | 4/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | RXRG | P48443 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062964 | 0.85 | PPARA (0.56) | PPARAPPARGRXRARXRBPPARD | |
| Lodinixil SCHEMBL3238255 | 0.82 | PPARA (0.54) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL10997716 | 0.82 | PPARA (0.67) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL31484148 | 0.81 | NUDT1 (0.49) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL10997171 | 0.80 | PPARA (0.55) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL1062227 | 0.79 | PPARA (0.48) | PPARAPPARGRXRARXRBPPARD | |
| Acetic Acid SCHEMBL3773388 | 0.78 | PPARA (0.61) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL3380949 | 0.77 | PPARA (0.67) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL11203409 | 0.77 | PPARA (0.48) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL11101428 | 0.77 | KMT2A (0.71) | PPARAPPARGRXRARXRBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4559345-A | Pyrimidine and s-triazine derivatives with antilipidemic activity | LBP ISTITUTO FARACEUTICO S.P.A. (IT) | 1985-12-17 | — | — | US | disclosed |
| EP-0073328-A1 | Novel pyrimidine and s. triazine derivatives with antilipidemic activity | LPB Istituto Farmaceutico s.p.a. (IT) | 1983-03-09 | — | — | EP | disclosed |