Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 12/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | RXRA | P19793 | 7/20 | 0.45 |
| ▸ | RXRB | P28702 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | RXRG | P48443 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484197 | 0.89 | SLC2A1 (0.47) | NUDT1KDM4EKMT2ALMNAGAA | |
| SCHEMBL31484173 | 0.85 | KDM4E (0.40) | KDM4EKMT2AMAPTALDH1A1SLC2A1 | |
| SCHEMBL31484099 | 0.82 | NUDT1 (0.50) | NUDT1KDM4EKMT2ALMNAGAA | |
| SCHEMBL10997703 | 0.81 | PPARA (0.58) | NUDT1KDM4EKMT2ALMNAGAA | |
| SCHEMBL31484248 | 0.80 | KMT2A (0.50) | KDM4EKMT2AMAPTMAPK1MEN1 | |
| SCHEMBL31484110 | 0.78 | MAPK10 (0.43) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL31484063 | 0.78 | ALDH1A1 (0.41) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL31484130 | 0.77 | MAPT (0.56) | KDM4EKMT2ALMNAGAAMAPT | |
| SCHEMBL31484220 | 0.77 | NFKB1 (0.56) | KMT2ALMNAMAPTPPARAPPARG | |
| SCHEMBL23754826 | 0.74 | ULK1 (0.46) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431324-A | 1- (4/5-Cyano-6-substituted pyrimidine-2-yl) -1H-pyrazole-4-formic acid compound, and preparation method and application thereof | 沈阳药科大学 | 2025-02-14 | — | — | CN | disclosed |