Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.48 |
| ▸ | PPARG | P37231 | 12/20 | 0.48 |
| ▸ | RXRA | P19793 | 6/20 | 0.48 |
| ▸ | RXRB | P28702 | 5/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997703 | 0.79 | PPARA (0.58) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL375419 | 0.75 | ULK1 (0.51) | — | |
| SCHEMBL12311824 | 0.71 | ULK1 (0.57) | — | |
| SCHEMBL353666 | 0.70 | L3MBTL1 (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL11101428 | 0.70 | KMT2A (0.71) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL12571001 | 0.69 | ULK1 (0.47) | KMT2A | |
| Acetic Acid SCHEMBL3773388 | 0.68 | PPARA (0.61) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL23718206 | 0.68 | MEN1 (0.57) | KDM4EMEN1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4572913 | 0.68 | KMT2A (0.42) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL18153262 | 0.67 | SLC2A1 (0.53) | PPARAPPARGRXRARXRBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275413-A1 | 2,4-di(phenylamino)-pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders. | Novartis AG (CH) | 2011-01-19 | — | — | EP | disclosed |