Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5572443 | 0.87 | PTGS2 (0.59) | PTGS2HTR2AHTR2CHTR2BTUBB4A | |
| Pregomisin SCHEMBL29045386 | 0.87 | ALOX15 (0.62) | PTGS2FOSTTRJUNNR3C1 | |
| SCHEMBL4962257 | 0.85 | PTGS2 (0.48) | PTGS2FOSTTRJUNNR3C1 | |
| SCHEMBL394373 | 0.83 | PTGS2 (0.55) | PTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL20553334 | 0.83 | PTGS2 (0.55) | PTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL394374 | 0.83 | PTGS2 (0.55) | PTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL31643539 | 0.83 | PTGS2 (0.55) | PTGS2FOSTTRJUNNR3C1 | |
| SCHEMBL4106588 | 0.83 | PTGS2 (0.55) | PTGS2FOSTTRJUNNR3C1 | |
| SCHEMBL31644059 | 0.83 | PTGS2 (0.55) | PTGS2FOSTTRJUNNR3C1 | |
| Hydrochloric Acid SCHEMBL35210353 | 0.82 | PTGS2 (0.53) | PTGS2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562298-A | Optically active nordihydroguaiaretic acid and intermediates | CHEMEX PHARMACEUTICALS, INC. (US) | 1985-12-31 | — | — | US | disclosed |