Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992876 | 0.80 | KIF11 (0.39) | KIF11CYP2D6KMT2AMEN1CYP3A4 | |
| SCHEMBL10998615 | 0.79 | KIF11 (0.42) | KIF11CYP1A2CYP2D6KMT2AMEN1 | |
| SCHEMBL6535389 | 0.76 | KCNN4 (0.42) | KIF11CYP1A2CYP2D6KMT2AKCNN4 | |
| SCHEMBL10997363 | 0.73 | KIF11 (0.42) | KIF11CYP1A2CYP2D6KMT2AMEN1 | |
| Pyridine SCHEMBL8673561 | 0.69 | CYP1A2 (0.39) | KIF11CYP1A2CYP2D6KMT2AMEN1 | |
| SCHEMBL28320432 | 0.69 | CYP19A1 (0.54) | KIF11CYP17A1CYP19A1 | |
| SCHEMBL8695362 | 0.67 | KIF11 (0.46) | KIF11CYP1A2CYP2D6KMT2AMEN1 | |
| SCHEMBL10793742 | 0.67 | ELANE (0.39) | KIF11CYP1A2CYP2D6KMT2AMEN1 | |
| SCHEMBL4905934 | 0.67 | ELANE (0.39) | KIF11CYP1A2CYP2D6KMT2AMEN1 | |
| SCHEMBL10958637 | 0.67 | ELANE (0.39) | KIF11CYP1A2CYP2D6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4535084-A | ANTIARTHRITIC, ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4246263-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1981-01-20 | — | — | US | disclosed |