Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518706 | 0.78 | SLC6A4 (0.49) | PPARAPPARGSLC6A4FFAR1SLC6A9 | |
| SCHEMBL13953755 | 0.77 | ALDH1A1 (0.48) | PPARAPPARGSLC6A4FFAR1KMT2A | |
| SCHEMBL11003778 | 0.77 | PPARA (0.47) | PPARAPPARGSLC6A4FFAR1SLC6A9 | |
| SCHEMBL31664416 | 0.74 | ACACB (0.48) | PPARAPPARG | |
| SCHEMBL2232687 | 0.74 | FFAR1 (0.41) | PPARAPPARGSLC6A4FFAR1KMT2A | |
| Alcohol SCHEMBL20495951 | 0.73 | IDO1 (0.46) | SLC6A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11960419 | 0.72 | ALDH1A1 (0.42) | SLC6A4FFAR1KMT2ACNR2SLC6A9 | |
| SCHEMBL20591074 | 0.72 | LTA4H (0.65) | PPARAPPARG | |
| SCHEMBL11360054 | 0.71 | SLC6A4 (0.57) | PPARAPPARGSLC6A4FFAR1SLC6A9 | |
| SCHEMBL3524687 | 0.71 | NOS2 (0.50) | SLC6A4KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556715-A | ANTILIPEMIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1985-12-03 | — | — | US | disclosed |