SCHEMBL11001076

SCHEMBL11001076

COCCOCCOCCNC(=O)n1c(CNC(=O)O)nc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 7/20 0.47
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
TP53 P04637 1/20 0.43
LMNA P02545 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10999430 0.85 SMN1; SMN2 (0.36) ASAH1ALDH1A1TSHRSMN1; SMN2
SCHEMBL10999212 0.85 SMN1; SMN2 (0.36) ASAH1ALDH1A1TSHRSMN1; SMN2
SCHEMBL28386901 0.83 ASAH1 (0.54) ASAH1ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL22798839 0.81 ASAH1 (0.61) ASAH1ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL28427150 0.81 ASAH1 (0.49) ASAH1ALDH1A1TSHR
SCHEMBL11006802 0.80 ALDH1A1 (0.71) ASAH1ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL28385261 0.80 ASAH1 (0.48) ASAH1ALDH1A1TSHRMEN1KMT2A
SCHEMBL28893309 0.79 ALDH1A1 (0.56) ASAH1ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL28385921 0.78 ALDH1A1 (0.57) ASAH1ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL28426062 0.74 ALDH1A1 (0.43) ASAH1ALDH1A1TSHRSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4560738-A REACTION OF ACTIVE HYDROGEN PESTICIDE WITH POLYETHER ISOCYANATE BAYER AKTIENGESELLSCHAFT (DE) 1985-12-24 US claimed