SCHEMBL28385261

SCHEMBL28385261

CCCNC(=O)n1c(COCCNC(=O)O)nc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 8/20 0.48
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CNR2 P34972 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28385921 0.94 ALDH1A1 (0.57) ASAH1TSHRALDH1A1CYP1A2CYP3A4
SCHEMBL28427150 0.90 ASAH1 (0.49) ASAH1TSHRALDH1A1CNR2POLB
SCHEMBL28893309 0.84 ALDH1A1 (0.56) ASAH1TSHRALDH1A1CNR2
SCHEMBL28386901 0.84 ASAH1 (0.54) ASAH1TSHRALDH1A1MEN1KMT2A
SCHEMBL11001076 0.80 ASAH1 (0.47) ASAH1TSHRALDH1A1MEN1KMT2A
SCHEMBL29397039 0.79 TSHR (0.51) ASAH1TSHRALDH1A1CNR2POLB
SCHEMBL22798839 0.77 ASAH1 (0.61) ASAH1TSHRALDH1A1MEN1KMT2A
SCHEMBL28385573 0.76 TSHR (0.42) TSHRALDH1A1KMT2APOLB
SCHEMBL5570257 0.76 TSHR (0.67) ASAH1TSHRALDH1A1CYP1A2MEN1
SCHEMBL28426062 0.75 ALDH1A1 (0.43) ASAH1TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195596-B Branched organosilicon compounds, methods of making branched organosilicon compounds, and compositions comprising branched organosilicon compounds 美国陶氏有机硅公司 2023-02-28 CN disclosed
CN-113330054-B Branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2023-02-21 CN disclosed
CN-113348199-B Branched organosilicon compounds, methods of making branched organosilicon compounds, and copolymers formed therewith 美国陶氏有机硅公司 2023-02-17 CN disclosed
CN-113166423-B Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2023-02-17 CN disclosed
CN-110177847-B Emulsions, compositions comprising emulsions, films formed therefrom, and related methods 美国陶氏有机硅公司 2022-04-19 CN disclosed
CN-110997757-B Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods 美国陶氏有机硅公司 2022-03-08 CN disclosed
CN-113348174-A Branched organosilicon compounds, methods of making the branched organosilicon compounds, and related compositions 美国陶氏有机硅公司 2021-09-03 CN disclosed
CN-113348199-A Branched organosilicon compounds, methods of making branched organosilicon compounds, and copolymers formed therewith 美国陶氏有机硅公司 2021-09-03 CN disclosed
CN-113330054-A Branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2021-08-31 CN disclosed
CN-113330055-A Acrylate-functional branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2021-08-31 CN disclosed
CN-113195596-A Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2021-07-30 CN disclosed
CN-113195507-A Multifunctional organosilicon compounds and related methods, compounds, and compositions 美国陶氏有机硅公司 2021-07-30 CN disclosed
CN-113166423-A Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2021-07-23 CN disclosed
CN-107207546-B Ligand component, related reaction product, activated reaction product, composition containing same and preparation method thereof 美国陶氏有机硅公司 2020-06-09 CN disclosed
CN-110997757-A Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods 美国陶氏有机硅公司 2020-04-10 CN disclosed