SCHEMBL28386901

SCHEMBL28386901

CCCNC(=O)n1c(CNC(=O)O)nc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 7/20 0.54
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
TP53 P04637 1/20 0.48
MAPK1 P28482 1/20 0.48
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22798839 0.93 ASAH1 (0.61) ASAH1MEN1KMT2AALDH1A1TSHR
SCHEMBL28426062 0.87 ALDH1A1 (0.43) ASAH1MEN1KMT2AALDH1A1TSHR
SCHEMBL27980384 0.86 ASAH1 (0.49) ASAH1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL28385261 0.84 ASAH1 (0.48) ASAH1MEN1KMT2AALDH1A1TSHR
SCHEMBL28427150 0.83 ASAH1 (0.49) ASAH1ALDH1A1TSHRPOLB
SCHEMBL11001076 0.83 ASAH1 (0.47) ASAH1MEN1KMT2AALDH1A1TSHR
SCHEMBL5570257 0.81 TSHR (0.67) ASAH1MEN1KMT2AALDH1A1TSHR
SCHEMBL29397039 0.81 TSHR (0.51) ASAH1ALDH1A1TSHRSMN1; SMN2POLB
SCHEMBL28313419 0.79 ASAH1 (0.81) ASAH1MEN1KMT2AALDH1A1TSHR
Carbamic Acid SCHEMBL7102690 0.78 ASAH1 (0.64) ASAH1ALDH1A1TSHRSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177847-B Emulsions, compositions comprising emulsions, films formed therefrom, and related methods 美国陶氏有机硅公司 2022-04-19 CN disclosed
CN-110997757-B Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods 美国陶氏有机硅公司 2022-03-08 CN disclosed
CN-113348174-A Branched organosilicon compounds, methods of making the branched organosilicon compounds, and related compositions 美国陶氏有机硅公司 2021-09-03 CN disclosed
CN-113348199-A Branched organosilicon compounds, methods of making branched organosilicon compounds, and copolymers formed therewith 美国陶氏有机硅公司 2021-09-03 CN disclosed
CN-113330055-A Acrylate-functional branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2021-08-31 CN disclosed
CN-113330054-A Branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2021-08-31 CN disclosed
CN-113195596-A Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2021-07-30 CN disclosed
CN-113195507-A Multifunctional organosilicon compounds and related methods, compounds, and compositions 美国陶氏有机硅公司 2021-07-30 CN disclosed
CN-113166423-A Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2021-07-23 CN disclosed
CN-107207546-B Ligand component, related reaction product, activated reaction product, composition containing same and preparation method thereof 美国陶氏有机硅公司 2020-06-09 CN disclosed
CN-110997757-A Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods 美国陶氏有机硅公司 2020-04-10 CN disclosed