Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001287 | 1.00 | LMNA (0.40) | LMNAKDM4EL3MBTL1TRPA1HRH1 | |
| SCHEMBL9656453 | 0.81 | LMNA (0.46) | LMNAKDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL9656438 | 0.81 | LMNA (0.46) | LMNAKDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL2243794 | 0.81 | LMNA (0.48) | LMNAKDM4EL3MBTL1TRPA1AOC3 | |
| SCHEMBL96430 | 0.81 | LMNA (0.48) | LMNAKDM4EL3MBTL1TRPA1AOC3 | |
| SCHEMBL2170476 | 0.81 | TRPA1 (0.53) | LMNAKDM4ETRPA1AOC3ALDH1A1 | |
| SCHEMBL2170478 | 0.81 | TRPA1 (0.53) | LMNAKDM4ETRPA1AOC3ALDH1A1 | |
| SCHEMBL7057351 | 0.79 | AOC3 (0.38) | KDM4ETRPA1AOC3TSHR | |
| SCHEMBL7059435 | 0.79 | TSHR (0.51) | LMNAMAPK1AOC3TSHRSLC6A4 | |
| SCHEMBL10999062 | 0.79 | STAT3 (0.35) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560769-A | CATALYTIC CYCLIZATION OF AMMONIA OR AMINE WITH BUT-2-ENE-1,4-DIOL | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| US-3975381-A | Process for preparing γ-lactone derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1976-08-17 | — | — | US | disclosed |