SCHEMBL11004686

SCHEMBL11004686

CC(CN1CCOCC1)C(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
LMNA P02545 6/20 0.69
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
SIGMAR1 Q99720 3/20 0.53
CHRM2 P08172 2/20 0.53
ADRA2B P18089 2/20 0.53
DRD3 P35462 2/20 0.53
HRH3 Q9Y5N1 2/20 0.53
CYP2D6 P10635 1/20 0.51
ADRA2C P18825 1/20 0.51
CHRM3 P20309 1/20 0.51
OPRD1 P41143 1/20 0.51
KCNH2 Q12809 1/20 0.51
MAPT P10636 5/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
RAB9A P51151 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
NPC1 O15118 1/20 0.49
MITF O75030 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11076147 0.99 ALDH1A1 (0.71) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL13058950 0.88 ALDH1A1 (0.67) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL9168033 0.87 CHRM2 (0.69) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL10851001 0.86 SIGMAR1 (0.72) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL10850475 0.85 ALDH1A1 (0.74) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL14384871 0.83 ALDH1A1 (0.72) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL11946057 0.83 ALDH1A1 (0.72) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL10584214 0.83 ALDH1A1 (0.97) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL9175526 0.82 CHRM2 (0.75) ALDH1A1LMNAMEN1KMT2ASIGMAR1
SCHEMBL11089106 0.82 MEN1 (0.57) ALDH1A1LMNAMEN1KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4495184-A Morpholino propanol derivatives, fungicidal compositions and use BAYER AKTIENGESELLSCHAFT (DE) 1985-01-22 US disclosed
EP-0040740-B1 AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1984-11-14 EP disclosed
US-4465678-A Aminopropiophenone derivatives and fungicidal use BAYER AKTIENGESELLSCHAFT (DE) 1984-08-14 US disclosed
EP-0040744-B1 AMINOPROPIOPHENONE OXIMES, PROCESSES FOR PREPARING THEM AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1984-02-08 EP disclosed
EP-0040744-A1 Aminopropiophenone oximes, processes for preparing them and their use as fungicides BAYER AG (DE) 1981-12-02 EP disclosed