Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 9/20 | 0.41 |
| ▸ | CA1 | P00915 | 9/20 | 0.41 |
| ▸ | CA2 | P00918 | 9/20 | 0.41 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 6/20 | 0.40 |
| ▸ | CA5A | P35218 | 6/20 | 0.40 |
| ▸ | CA7 | P43166 | 6/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426234 | 0.83 | TSHR (0.45) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL10999362 | 0.82 | TSHR (0.50) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL3815688 | 0.82 | TSHR (0.53) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL1846805 | 0.80 | TSHR (0.52) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL9232014 | 0.76 | TSHR (0.48) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL8595566 | 0.75 | TSHR (0.47) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL8595649 | 0.75 | TSHR (0.47) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL9232024 | 0.75 | TSHR (0.47) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL6884785 | 0.74 | ALDH1A1 (0.52) | TSHRPTPN1ALDH1A1LMNATHRB | |
| SCHEMBL11407341 | 0.74 | TSHR (0.54) | TSHRPTPN1ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-A2 | Novel cyanoimidazole nucleoside derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1985-09-18 | — | — | EP | disclosed |