Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949649 | 0.88 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL9022060 | 0.81 | CYP3A4 (0.45) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL10407825 | 0.77 | EGLN3 (0.40) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL950886 | 0.77 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL10680117 | 0.76 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL10869615 | 0.74 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27975527 | 0.74 | EGLN3 (0.42) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11096568 | 0.72 | EGLN3 (0.47) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11350755 | 0.72 | CYP3A4 (0.48) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9824026 | 0.72 | CYP1A2 (0.44) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549900-A | PLANT GROWTH REGULATOR | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-29 | — | — | US | claimed |