SCHEMBL1100511

SCHEMBL1100511

CC(C)C=C1C(=O)c2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.54
ALDH1A1 P00352 8/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
HTT P42858 4/20 0.54
HIF1A Q16665 2/20 0.54
KMT2A Q03164 7/20 0.50
MEN1 O00255 4/20 0.50
CDC25B P30305 3/20 0.50
NFKB1 P19838 1/20 0.49
CASP3 P42574 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
POLB P06746 4/20 0.48
RAB9A P51151 3/20 0.48
KDM4E B2RXH2 3/20 0.48
LMNA P02545 3/20 0.48
S100A4 P26447 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20821321 0.86 MAPT (0.46) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL19759280 0.86 MAPT (0.46) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL1104969 0.77 KMT2A (0.39) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL1104624 0.75 MAPT (0.58) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL14431153 0.75 MAPT (0.58) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL23095433 0.71 MAPT (0.54) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL10637943 0.71 MAPT (0.48) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL9611565 0.71 ALDH1A1 (0.41) MAPTALDH1A1KMT2AMEN1NFKB1
SCHEMBL23730605 0.71 S100A4 (0.56) MAPTALDH1A1SMN1; SMN2HTTHIF1A
SCHEMBL10600278 0.70 KMT2A (0.55) MAPTALDH1A1SMN1; SMN2HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220407015-A1 MOLECULAR MATERIALS BASED ON PHENOXYAZINE CORE FOR HETEROJUNCTION ORGANIC SOLAR CELLS SUMITOMO CHEMICAL CO., LTD. (JP) 2022-12-22 US disclosed
EP-3812383-A1 MOLECULAR MATERIALS BASED ON PHENOXYAZINE CORE FOR HETEROJUNCTION ORGANIC SOLAR CELLS Sumitomo Chemical Co., Ltd (JP) 2021-04-28 EP disclosed
US-10236457-B2 Synthesis of porphyrin materials for highly efficient organic photovoltaics HONG KONG BAPTIST UNIVERSITY (HK) 2019-03-19 US disclosed
US-20190049838-A1 Photosensitive Microcapsules ENCAPSYS, LLC 2019-02-14 US disclosed
US-20180006248-A1 Design and synthesis of porphyrin materials for highly efficient organic photovoltaics HONG KONG BAPTIST UNIVERSITY (HK) 2018-01-04 US disclosed
EP-2695874-A1 Myrtucommulone analogues Universität des Saarlandes (DE) 2014-02-12 EP disclosed
EP-2695874-A1 Myrtucommulone analogues Universität des Saarlandes (DE) 2014-02-12 EP disclosed
US-8152861-B2 Dark coloured azo dyes THE PROCTER & GAMBLE COMPANY (US) 2012-04-10 US disclosed
US-8152861-B2 Dark coloured azo dyes THE PROCTER & GAMBLE COMPANY (US) 2012-04-10 US disclosed
US-20110225742-A1 Dark Coloured Azo Dyes WELLA OPERATIONS US, LLC 2011-09-22 US disclosed
US-20110225742-A1 Dark Coloured Azo Dyes WELLA OPERATIONS US, LLC 2011-09-22 US disclosed
US-7977482-B2 Dark coloured azo dyes THE PROCTER & GAMBLE COMPANY (US) 2011-07-12 US disclosed
US-7977482-B2 Dark coloured azo dyes THE PROCTER & GAMBLE COMPANY (US) 2011-07-12 US disclosed
US-20090118510-A1 Dark coloured azo dyes WELLA OPERATIONS US, LLC 2009-05-07 US disclosed
US-20090118510-A1 Dark coloured azo dyes WELLA OPERATIONS US, LLC 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220407015-A1 MOLECULAR MATERIALS BASED ON PHENOXYAZINE CORE FOR HETEROJUNCTION ORGANIC SOLAR CELLS ESRRG, OR10J3, KCNJ5 MAPT 3786/4885ALDH1A1 1615/4885SMN1; SMN2 4744/4885
US-20090118510-A1 Dark coloured azo dyes KRT18, CYB5R3, CYBA MAPT 1859/4885ALDH1A1 709/4885SMN1; SMN2 4877/4885
US-20110225742-A1 Dark Coloured Azo Dyes KRT18, CYB5R3, CYBA MAPT 1859/4885ALDH1A1 709/4885SMN1; SMN2 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.