Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385752 | 0.91 | ACE (0.46) | ACE | |
| SCHEMBL9725898 | 0.83 | OPRD1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL7634867 | 0.82 | OPRD1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7634870 | 0.82 | OPRD1 (0.38) | — | |
| SCHEMBL11001562 | 0.82 | ACE (0.51) | ACE | |
| SCHEMBL11006771 | 0.81 | — | — | |
| SCHEMBL11006403 | 0.81 | — | — | |
| SCHEMBL11006979 | 0.81 | — | — | |
| SCHEMBL27280950 | 0.81 | AHCY (0.36) | — | |
| SCHEMBL27280948 | 0.81 | AHCY (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035868-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-16 | — | — | EP | claimed |
| US-4521607-A | HYPOTENSIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0035868-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-16 | — | — | EP | disclosed |
| US-4256761-A | Antihypertensive amides | USV PHARMACEUTICAL CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |