Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005113 | 0.91 | ACE (0.47) | ACE | |
| SCHEMBL9726022 | 0.85 | HTR1A (0.44) | — | |
| SCHEMBL11000681 | 0.84 | ACE (0.49) | ACE | |
| SCHEMBL11007480 | 0.84 | DRD2 (0.49) | — | |
| SCHEMBL11365002 | 0.77 | — | — | |
| SCHEMBL11007928 | 0.77 | ALDH1A1 (0.48) | ACE | |
| SCHEMBL11374701 | 0.76 | — | — | |
| SCHEMBL9725898 | 0.76 | OPRD1 (0.39) | — | |
| SCHEMBL13209062 | 0.75 | HTR1A (0.51) | — | |
| SCHEMBL10923490 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035868-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-16 | — | — | EP | claimed |