Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042095 | 0.87 | LTA4H (0.40) | ALDH1A1LMNARAB9ACES2CES1 | |
| SCHEMBL11045583 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNASRD5A2RAB9AHPGD | |
| SCHEMBL16574290 | 0.73 | BCL2L11 (0.61) | — | |
| SCHEMBL11006723 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNASRD5A2RAB9AHPGD | |
| SCHEMBL15140049 | 0.72 | BCL2L11 (0.54) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL822185 | 0.70 | ALDH1A1 (1.00) | ALDH1A1LMNASRD5A2RAB9AHPGD | |
| SCHEMBL52200 | 0.70 | ALDH1A1 (1.00) | ALDH1A1LMNASRD5A2RAB9AHPGD | |
| SCHEMBL8606636 | 0.69 | ALDH1A1 (0.46) | ALDH1A1LMNASRD5A2RAB9AHPGD | |
| SCHEMBL195263 | 0.69 | ALDH1A1 (0.76) | ALDH1A1LMNASRD5A2RAB9AHPGD | |
| SCHEMBL14135917 | 0.69 | ALDH1A1 (0.76) | ALDH1A1LMNASRD5A2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505927-A | ANTINFLAMMATORY AGENTS, ANALGESICS, ANTIPRETICS | SYNTEX (U.S.A.) INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4456759-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTICOAGULANTS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4347185-A | DECARBOXYLATION OF THE 1,1-DICARBOXYLATES | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |