Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005116 | 0.86 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL15140049 | 0.79 | BCL2L11 (0.54) | ALDH1A1MAPTLMNAALOX15HPGD | |
| SCHEMBL11006234 | 0.77 | CNR1 (0.42) | ALDH1A1L3MBTL1HPGDTYMPCES2 | |
| SCHEMBL15151250 | 0.75 | MCL1 (0.53) | ALDH1A1MAPTLMNARAB9AMEN1 | |
| SCHEMBL8343752 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAALOX15MEN1 | |
| Acetic Acid SCHEMBL29024346 | 0.71 | MAPT (0.43) | ALDH1A1MAPTLMNARAB9AMEN1 | |
| SCHEMBL11694243 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNARAB9AMEN1 | |
| SCHEMBL8447111 | 0.69 | KDM4E (0.47) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4783318 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAALOX15RAB9A | |
| SCHEMBL7339717 | 0.68 | PDE4A (0.66) | ALDH1A1MAPTALOX15RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456759-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTICOAGULANTS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4347185-A | DECARBOXYLATION OF THE 1,1-DICARBOXYLATES | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |