Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PPOX | P50336 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220963 | 0.88 | LMNA (0.52) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL11003625 | 0.88 | TDP1 (0.49) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL10452504 | 0.85 | KMT2A (0.69) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL11455024 | 0.85 | KMT2A (0.61) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| Potassium Ion SCHEMBL11458215 | 0.84 | KMT2A (0.56) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL10775218 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL11455998 | 0.84 | KMT2A (0.56) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL11008594 | 0.84 | RAB9A (0.54) | LMNAKMT2AMEN1TDP1TTR | |
| SCHEMBL11004074 | 0.84 | MEN1 (0.73) | SMN1; SMN2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL10772903 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556413-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-12-03 | — | — | US | claimed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | claimed |
| US-4556413-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-12-03 | — | — | US | disclosed |