Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009667 | 1.00 | TP53 (0.41) | TP53CYP3A4ALOX15TYRHTT | |
| SCHEMBL11005595 | 1.00 | TP53 (0.41) | TP53CYP3A4ALOX15TYRHTT | |
| SCHEMBL11001796 | 0.94 | OPRM1 (0.40) | TP53CYP3A4ALOX15TYRHTT | |
| SCHEMBL11004077 | 0.80 | ALDH1A1 (0.39) | CYP3A4HTTMEN1MAPTKMT2A | |
| SCHEMBL11001228 | 0.80 | PTGS1 (0.44) | CYP3A4ALOX15MAPTTSHRKMT2A | |
| SCHEMBL11005383 | 0.80 | ALDH1A1 (0.39) | CYP3A4HTTMEN1MAPTKMT2A | |
| SCHEMBL11005871 | 0.80 | ALDH1A1 (0.39) | CYP3A4HTTMEN1MAPTKMT2A | |
| SCHEMBL11004277 | 0.78 | ALDH1A1 (0.40) | CYP3A4HTTMEN1MAPTKMT2A | |
| SCHEMBL11005275 | 0.77 | ALOX5 (0.40) | HTTMEN1ALOX5MAPTKMT2A | |
| SCHEMBL11008518 | 0.77 | ALOX5 (0.40) | HTTMEN1ALOX5MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499115-A | FOR FOODS | UNISEARCH LIMITED (AU) | 1985-02-12 | — | — | US | disclosed |