SCHEMBL1100536

SCHEMBL1100536

O=[N+]([O-])c1ccc(Cl)c2onnc12

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
IDO1 P14902 3/20 0.42
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
VCAM1 P19320 5/20 0.37
MAPT P10636 2/20 0.35
GSTP1 P09211 1/20 0.35
GSTM2 P28161 1/20 0.35
HSD17B10 Q99714 1/20 0.34
PDE7A Q13946 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2313725 0.87 TDP1 (0.46) ALDH1A1TDP1IDO1TSHRMAPK1
SCHEMBL2310322 0.83 TDP1 (0.41) ALDH1A1TDP1IDO1TSHRMAPK1
SCHEMBL2333611 0.80 TDP1 (0.41) ALDH1A1TDP1IDO1TSHRMAPK1
SCHEMBL28078442 0.77 MAPT (0.41) ALDH1A1TDP1TSHRMAPK1MEN1
SCHEMBL7066582 0.76 LMNA (0.49) ALDH1A1TDP1IDO1MAPK1MEN1
SCHEMBL7207029 0.73 ALDH1A1 (0.50) ALDH1A1TDP1IDO1TSHRMAPK1
SCHEMBL5059455 0.73 TDP1 (0.46) ALDH1A1TDP1IDO1TSHRMAPK1
SCHEMBL3203718 0.73 TDP1 (0.41) ALDH1A1TDP1IDO1TSHRMAPK1
SCHEMBL31658972 0.73 GSTP1 (0.46) ALDH1A1TDP1IDO1MAPK1MEN1
SCHEMBL17209987 0.73 PARP1 (0.35) ALDH1A1TDP1IDO1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050250170-A1 Determination of metal ions in solution by photoluminescence anisotropy THOMPSON, RICHARD B. 2005-11-10 US claimed
US-20020055091-A1 Determination of metal ions in solution by photoluminescence anisotropy UNIVERSITY OF PENNSYLVANIA 2002-05-09 US claimed
JP-H08502725-A 1996-03-26 JP claimed
EP-0654999-A1 USE OF INHIBITORS OF VACUOLAR-TYPE H?+ ATPASES BIOCINE S.p.A. (IT) 1995-05-31 EP claimed
WO-1994004161-A1 USE OF INHIBITORS OF VACUOLAR-TYPE H+ ATPASES BIOCINE S.P.A. (IT) 1994-03-03 WO claimed
JP-10084943-A None JP disclosed
JP-63026638-A None JP disclosed
EP-3283879-B1 METHOD FOR DETECTING ONE OR MORE ANALYTES IN A SAMPLE, SAID DETECTION BEING DELIMITED BY A REACTION CHAMBER ATTOMOL GMBH MOLEKULARE DIAGNOSTIKA (DE) 2019-03-27 EP disclosed
EP-3283879-A1 METHOD FOR DETECTING ONE OR MORE ANALYTES IN A SAMPLE, SAID DETECTION BEING DELIMITED BY A REACTION CHAMBER Attomol GmbH Molekulare Diagnostika (DE) 2018-02-21 EP disclosed
WO-2016166295-A1 METHOD FOR DETECTING ONE OR MORE ANALYTES IN A SAMPLE, SAID DETECTION BEING DELIMITED BY A REACTION CHAMBER ATTOMOL GMBH MOLEKULARE DIAGNOSTIKA (DE) 2016-10-20 WO disclosed
EP-2183230-B9 NOVEL FLUORESCENT DERIVATIVES OF POLYAMINE, METHOD FOR PREPARING SAME AND APPLICATIONS THEREOF AS DIAGNOSIS TOOLS IN THE TREATMENT OF CANCEROUS TUMOURS PF MEDICAMENT (FR) 2015-09-02 EP disclosed
EP-2167964-B1 METHOD FOR CARRYING OUT AND EVALUATING MIX&MEASURE ASSAYS FOR THE MEASUREMENT OF REACTION KINETICS, CONCENTRATIONS AND AFFINITIES OF ANALYTES IN MULTIPLEX FORMAT ATTOMOL GMBH MOLEKULARE DIAGNOSTIKA (DE) 2015-03-11 EP disclosed
EP-0654999-A1 USE OF INHIBITORS OF VACUOLAR-TYPE H?+ ATPASES BIOCINE S.p.A. (IT) 1995-05-31 EP disclosed
WO-1994004161-A1 USE OF INHIBITORS OF VACUOLAR-TYPE H+ ATPASES BIOCINE S.P.A. (IT) 1994-03-03 WO disclosed
EP-0384364-B1 A composition of nonlinear optical materials and a method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1994-01-19 EP disclosed
US-5154858-A Mixture of 2-(p-chlorophenyl)imidazoline and a compound having an electron donative and an electron attractive group MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0487019-A2 Use of a nonlinear optical compound MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-05-27 EP disclosed
US-5009815-A Composition of nonlinear optical materials and a method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-04-23 US disclosed
EP-0384364-A2 A composition of nonlinear optical materials and a method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-08-29 EP disclosed
JP-S6326638-A NON-LINEAR OPTICAL ELEMENT NIPPON TELEGR & TELEPH CORP <NTT> 1988-02-04 JP disclosed