Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333611 | 0.87 | TDP1 (0.41) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL31658972 | 0.80 | GSTP1 (0.46) | TDP1ALDH1A1CASP6IDO1MAPT | |
| SCHEMBL2313725 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1VCAM1IDO1MAPT | |
| SCHEMBL30665014 | 0.75 | ALDH1A1 (0.38) | ALDH1A1CASP6MAPTLMNATSHR | |
| SCHEMBL29118433 | 0.75 | ALDH1A1 (0.38) | ALDH1A1CASP6MAPTLMNATSHR | |
| SCHEMBL6685709 | 0.74 | IDO1 (0.36) | ALDH1A1IDO1MAPTPOLBMEN1 | |
| SCHEMBL20836034 | 0.73 | TDP1 (0.41) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL1100536 | 0.73 | ALDH1A1 (0.46) | TDP1ALDH1A1VCAM1IDO1MAPT | |
| SCHEMBL2310322 | 0.73 | TDP1 (0.41) | TDP1ALDH1A1IDO1MAPTLMNA | |
| SCHEMBL3183161 | 0.73 | TDP1 (0.37) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029013-A1 | Methods for Detecting Asymmetric Dimethylarginine in a Biological Sample | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-04 | — | — | US | disclosed |
| US-7611844-B2 | Methods for detecting asymmetric dimethylarginine in a biological sample | BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) | 2009-11-03 | — | — | US | disclosed |
| US-20040214252-A1 | Methods for detecting asymmetric dimethylarginine in a biological sample | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-28 | — | — | US | disclosed |
| WO-2004046314-A2 | METHODS FOR DETECTING ASYMMETRIC DIMETHYLARGININE IN A BIOLOGICAL SAMPLE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029013-A1 | Methods for Detecting Asymmetric Dimethylarginine in a Biological Sample | ADM2, PADI3, PADI4 | TDP1 623/4885ATM 1529/4885ALDH1A1 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.