SCHEMBL1100543

SCHEMBL1100543

Nc1cc(Oc2cc(Oc3cc(N)cc(C(F)(F)F)c3)cc(C(F)(F)F)c2)cc(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
RAB9A P51151 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
NLRP3 Q96P20 1/20 0.42
F2 P00734 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
ST14 Q9Y5Y6 1/20 0.40
NR2E1 Q9Y466 1/20 0.37
IDO1 P14902 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KIF11 P52732 1/20 0.35
CES2 O00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7186658 0.98 ALDH1A1 (0.47) MAPTALDH1A1TSHRMAPK1RAB9A
Hydrochloric Acid SCHEMBL8952497 0.96 ALDH1A1 (0.45) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL7194629 0.92 RAB9A (0.48) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL7194344 0.92 RAB9A (0.48) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL30761013 0.91 MAPT (0.50) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL1100082 0.91 MAPT (0.50) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL14678305 0.88 RAB9A (0.46) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL7187662 0.88 NPC1 (0.55) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL7195569 0.87 KIF11 (0.47) MAPTALDH1A1TSHRMAPK1RAB9A
SCHEMBL8581109 0.87 MEN1 (0.58) MAPTALDH1A1TSHRMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5410084-A Diamine having perfluoro group; colorless, transparent, heat resistant,low dielectric constant MITSUI TOATSU CHEMICALS, INC. (JP) 1995-04-25 US claimed
EP-0565352-A2 Aromatic diamine and polyimde, and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-13 EP claimed
US-9735429-B2 Lithium ion secondary battery HITACHI, LTD. (JP) 2017-08-15 US disclosed
EP-2858150-B1 LITHIUM ION SECONDARY BATTERY HITACHI LTD (JP) 2017-03-15 EP disclosed
US-20150155563-A1 LITHIUM ION SECONDARY BATTERY HITACHI, LTD., (JP) 2015-06-04 US disclosed
EP-2858150-A1 LITHIUM ION SECONDARY BATTERY Hitachi, Ltd. (JP) 2015-04-08 EP disclosed
US-8153260-B2 Composite material ADEKA CORPORATION (JP) 2012-04-10 US disclosed
US-7851121-B2 Photosensitive polyimide composition and polyimide precursor composition CENTRAL GLASS CO., LTD. (JP) 2010-12-14 US disclosed
US-20100112323-A1 COMPOSITE MATERIAL ADEKA CORPORATION (JP) 2010-05-06 US disclosed
US-20090176172-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITION AND POLYIMIDE PRECURSOR COMPOSITION CENTRAL GLASS CO., LTD. (JP) 2009-07-09 US disclosed
WO-2007092011-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITION AND POLYIMIDE PRECURSOR COMPOSITION CENTRAL GLASS CO., LTD. (JP) 2007-08-16 WO disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed
EP-0822545-A2 Optical component and spirobiindan polymer therefor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed
EP-0565352-B1 Aromatic diamine and polyimide, and preparation process of same MITSUI TOATSU CHEMICALS (JP) 1997-07-30 EP disclosed
US-5578697-A DIELECTRIC POLYMERS FOR ELECTRONICS KABUSHIKI KAISHA TOSHIBA (JP) 1996-11-26 US disclosed
US-5410084-A Diamine having perfluoro group; colorless, transparent, heat resistant,low dielectric constant MITSUI TOATSU CHEMICALS, INC. (JP) 1995-04-25 US disclosed
US-5354839-A Low dielectric constant, colorless, transparent and excellent in processability and heat resistance MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-11 US disclosed
EP-0565352-A2 Aromatic diamine and polyimde, and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-13 EP disclosed