Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005557 | 0.92 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL8160692 | 0.84 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL11005567 | 0.72 | LMNA (0.44) | LMNANFKB1TSHRPMP22SLC22A6 | |
| Adipic Acid SCHEMBL27799608 | 0.69 | LMNA (0.58) | LMNANFKB1TSHRPMP22SLC22A6 | |
| SCHEMBL12048596 | 0.67 | TSHR (0.60) | LMNANFKB1TSHRPMP22SLC22A6 | |
| Adipic Acid SCHEMBL2244299 | 0.66 | LMNA (1.00) | LMNANFKB1TSHRPMP22SLC22A6 | |
| Adipic Acid SCHEMBL1330953 | 0.66 | LMNA (1.00) | LMNANFKB1TSHRPMP22SLC22A6 | |
| Adipic Acid SCHEMBL8941691 | 0.66 | LMNA (1.00) | LMNANFKB1TSHRPMP22SLC22A6 | |
| Adipic Acid SCHEMBL4930 | 0.66 | LMNA (1.00) | LMNANFKB1TSHRPMP22SLC22A6 | |
| Adipic Acid SCHEMBL25482 | 0.66 | LMNA (1.00) | LMNANFKB1TSHRPMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4540626-A | Polyhydroxyalkyl polycarbonamides for the production of flame-resistant polyurethane rigid foams and integral foams | BAYER AG (DE) | 1985-09-10 | — | — | US | claimed |