Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160700 | 0.84 | KMT2A (0.37) | PLA2G2CFAAHMEN1MAPK1KMT2A | |
| SCHEMBL20651727 | 0.73 | PLA2G10 (0.53) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL11005552 | 0.72 | LMNA (0.44) | LMNANFKB1TSHRPMP22SLC22A6 | |
| SCHEMBL18573713 | 0.71 | MEN1 (0.70) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL18573663 | 0.71 | MEN1 (0.70) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL23353370 | 0.71 | TSHR (0.52) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL20414825 | 0.71 | MEN1 (0.70) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL18837833 | 0.69 | PLA2G2C (0.54) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL15602821 | 0.69 | FAAH (0.60) | LMNANFKB1TSHRPMP22PLA2G2C | |
| SCHEMBL15602822 | 0.69 | FAAH (0.60) | LMNANFKB1TSHRPMP22PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4540626-A | Polyhydroxyalkyl polycarbonamides for the production of flame-resistant polyurethane rigid foams and integral foams | BAYER AG (DE) | 1985-09-10 | — | — | US | claimed |