Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668600 | 0.85 | KCNN4 (0.54) | KCNN4KIF11ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6844140 | 0.84 | KCNN4 (0.44) | KCNN4KIF11KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12762284 | 0.79 | KCNN4 (0.48) | KCNN4KIF11KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL14356119 | 0.79 | KIF11 (0.55) | KCNN4KIF11KCNH2SMN1; SMN2LTA4H | |
| SCHEMBL4363002 | 0.78 | KIF11 (0.49) | KCNN4KIF11KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12225852 | 0.78 | KIF11 (0.49) | KCNN4KIF11KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL14356107 | 0.76 | KIF11 (0.49) | KCNN4KIF11KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6746344 | 0.76 | KIF11 (0.71) | KCNN4KIF11KCNH2SMN1; SMN2LTA4H | |
| SCHEMBL2109881 | 0.76 | KCNN4 (0.46) | KCNN4KIF11KCNH2SMN1; SMN2LTA4H | |
| SCHEMBL30610089 | 0.76 | KIF11 (0.49) | KCNN4KIF11KCNH2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533497-A | N-ethylidene azetidinones | ELI LILLY AND COMPANY (US) | 1985-08-06 | — | — | US | disclosed |