Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005672 | 0.84 | PKM (0.48) | KCNN4KIF11KCNH2RAB9ANPC1 | |
| SCHEMBL6669392 | 0.82 | KCNN4 (0.48) | KCNN4KIF11RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6854126 | 0.81 | KIF11 (0.42) | KCNN4KIF11KCNH2RAB9ANPC1 | |
| SCHEMBL6750468 | 0.81 | KIF11 (0.42) | KCNN4KIF11KCNH2RAB9ANPC1 | |
| SCHEMBL30610089 | 0.79 | KIF11 (0.49) | KCNN4KIF11KCNH2RAB9ANPC1 | |
| SCHEMBL14356107 | 0.79 | KIF11 (0.49) | KCNN4KIF11KCNH2RAB9ANPC1 | |
| SCHEMBL12762284 | 0.79 | KCNN4 (0.48) | KCNN4KIF11KCNH2RAB9ANPC1 | |
| SCHEMBL14356119 | 0.79 | KIF11 (0.55) | KCNN4KIF11KCNH2SMN1; SMN2HTT | |
| SCHEMBL4363002 | 0.78 | KIF11 (0.49) | KCNN4KIF11KCNH2SMN1; SMN2HTT | |
| SCHEMBL12225852 | 0.78 | KIF11 (0.49) | KCNN4KIF11KCNH2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040019000-A1 | Polyalkyleneamine-containing oligomers | ISIS PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019000-A1 | Polyalkyleneamine-containing oligomers | FUS, NSF, PICALM | KCNN4 2440/4885KIF11 2034/4885KCNH2 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.