Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526311 | 0.84 | HTR1A (0.58) | HTR1A | |
| SCHEMBL9527472 | 0.83 | HTR1A (0.55) | HTR1A | |
| SCHEMBL9826970 | 0.83 | HTR1A (0.46) | HTR1AHRH3DRD2 | |
| SCHEMBL9828755 | 0.83 | — | — | |
| SCHEMBL9828750 | 0.83 | — | — | |
| SCHEMBL10661175 | 0.82 | HTR1A (0.56) | HTR1A | |
| SCHEMBL11004867 | 0.81 | DRD2 (0.72) | HTR1ADRD2DRD4 | |
| SCHEMBL9527844 | 0.81 | HTR1A (0.55) | HTR1A | |
| SCHEMBL9601724 | 0.81 | HTR1A (0.60) | HTR1AHRH3DRD2DRD4 | |
| SCHEMBL11002569 | 0.80 | DRD2 (0.49) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562255-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-12-31 | — | — | US | claimed |