Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527844 | 0.92 | HTR1A (0.55) | HTR1A | |
| SCHEMBL9527472 | 0.92 | HTR1A (0.55) | HTR1A | |
| SCHEMBL10661175 | 0.84 | HTR1A (0.56) | HTR1A | |
| SCHEMBL11005707 | 0.84 | HTR1A (0.56) | HTR1A | |
| SCHEMBL9527873 | 0.83 | — | — | |
| SCHEMBL13532600 | 0.83 | — | — | |
| Zalospirone SCHEMBL3374045 | 0.81 | DRD2 (0.72) | HTR1A | |
| Zalospirone SCHEMBL9526873 | 0.81 | DRD2 (0.72) | HTR1A | |
| Zalospirone SCHEMBL17256233 | 0.81 | DRD2 (0.72) | HTR1A | |
| Zalospirone SCHEMBL247562 | 0.81 | DRD2 (0.72) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | claimed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | claimed |
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | disclosed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | disclosed |