Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005766 | 0.91 | MAPT (0.55) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL11010896 | 0.86 | LMNA (0.50) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL9837374 | 0.86 | RAB9A (0.53) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL11011189 | 0.85 | TP53 (0.66) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL9569354 | 0.81 | MAPT (0.56) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL13394275 | 0.79 | MAPT (0.52) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL11011184 | 0.79 | TP53 (0.78) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL11010888 | 0.79 | LMNA (0.58) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL3875610 | 0.79 | LMNA (0.61) | MAPTLMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL24106082 | 0.78 | LMNA (0.70) | MAPTLMNATP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56068685-A | — | — | None | — | — | JP | disclosed |
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |
| JP-S5668685-A | 2-PHENYLIMIDAZO 2,1-B BENZOTHIAZOLE DERIVATIVE AND ITS PREPARATION | YAMANOUCHI PHARMACEUT CO LTD | 1981-06-09 | — | — | JP | disclosed |