Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011725 | 0.90 | MAPT (0.51) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL11005773 | 0.86 | MAPT (0.48) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL10806421 | 0.86 | MAPT (0.52) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL84416 | 0.85 | RAB9A (0.64) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL13394275 | 0.84 | MAPT (0.52) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL11005766 | 0.84 | MAPT (0.55) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL11012504 | 0.84 | MAPT (0.51) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL7763808 | 0.83 | MAPT (0.53) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL11010264 | 0.83 | MAPT (0.53) | RAB9ASMN1; SMN2LMNATP53MAPT | |
| SCHEMBL11011244 | 0.83 | TP53 (0.67) | RAB9ASMN1; SMN2LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | claimed |
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |
| EP-0082712-B1 | 2-PHENYLIMIDAZO(2,1-B)BENZOTHIAZOLE COMPOUNDS, SALTS THEREOF, PROCESS FOR PRODUCING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-06-16 | — | — | EP | disclosed |
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |
| US-4464384-A | SUPPRESSANTS OF IMMUNE RESPONSE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0082712-A2 | 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-06-29 | — | — | EP | disclosed |