Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402875 | 0.89 | KDM4E (0.49) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11008986 | 0.82 | RAB9A (0.53) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11005888 | 0.82 | LMNA (0.53) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11012106 | 0.81 | LMNA (0.52) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11008878 | 0.80 | LMNA (0.51) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11011663 | 0.80 | LMNA (0.51) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11008496 | 0.79 | LMNA (0.46) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11011702 | 0.78 | MAPT (0.49) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11007765 | 0.77 | LMNA (0.48) | LMNARAB9AMAPTHTTNPC1 | |
| SCHEMBL11011232 | 0.77 | LMNA (0.48) | LMNARAB9AMAPTHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |