Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006285 | 1.00 | HRH3 (0.39) | HRH3CYP2C9KCNH2ALDH1A1LMNA | |
| SCHEMBL11010385 | 0.93 | GBA1 (0.44) | HRH3KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL11010383 | 0.93 | GBA1 (0.44) | HRH3KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL10899249 | 0.84 | MAOB (0.47) | HRH3CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10899256 | 0.84 | MAOB (0.47) | HRH3CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL11010477 | 0.82 | MAOA (0.43) | HRH3CYP2C9KCNH2ALDH1A1LMNA | |
| SCHEMBL11010472 | 0.82 | MAOA (0.43) | HRH3CYP2C9KCNH2ALDH1A1LMNA | |
| SCHEMBL22383276 | 0.82 | TEAD1 (0.48) | ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL11010469 | 0.82 | MAOA (0.43) | HRH3CYP2C9KCNH2ALDH1A1LMNA | |
| SCHEMBL11060529 | 0.81 | MAOB (0.53) | HRH3CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131837-A1 | Liquid crystalline compounds | MERCK PATENT GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |