Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010383 | 1.00 | GBA1 (0.44) | GBA1KCNH2CCR3MEN1RAB9A | |
| SCHEMBL11006285 | 0.93 | HRH3 (0.39) | GBA1KCNH2MEN1KMT2AHRH3 | |
| SCHEMBL11006291 | 0.93 | HRH3 (0.39) | GBA1KCNH2MEN1KMT2AHRH3 | |
| SCHEMBL28594519 | 0.87 | GBA1 (0.55) | GBA1CCR3MEN1RAB9AKMT2A | |
| SCHEMBL10385271 | 0.86 | HRH3 (0.46) | PRMT6HRH3 | |
| SCHEMBL10385270 | 0.86 | HRH3 (0.46) | PRMT6HRH3 | |
| SCHEMBL9346730 | 0.84 | GBA1 (0.50) | GBA1KCNH2CCR3MEN1KMT2A | |
| SCHEMBL7513470 | 0.84 | GBA1 (0.50) | GBA1KCNH2CCR3MEN1KMT2A | |
| SCHEMBL11010515 | 0.84 | GBA1 (0.50) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL9346744 | 0.84 | GBA1 (0.50) | GBA1KCNH2CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131837-A1 | Liquid crystalline compounds | MERCK PATENT GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |