Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805564 | 0.75 | ALDH1A1 (0.46) | KDM4EGAACA1CA2CA9 | |
| SCHEMBL6204247 | 0.73 | KDM4E (0.43) | KDM4ECYP3A4LMNACA1CA2 | |
| SCHEMBL28436076 | 0.73 | KDM4E (0.43) | KDM4ECYP3A4LMNACA1CA2 | |
| SCHEMBL15920753 | 0.73 | KDM4E (0.40) | KDM4ECYP3A4LMNACA1CA2 | |
| SCHEMBL2335113 | 0.70 | KDM4E (0.41) | KDM4ECYP3A4LMNACA1CA2 | |
| SCHEMBL14966073 | 0.70 | KDM4E (0.47) | KDM4ELMNA | |
| SCHEMBL16209582 | 0.70 | KDM4E (0.47) | KDM4ELMNA | |
| SCHEMBL28173707 | 0.70 | KDM4E (0.41) | KDM4ELMNA | |
| SCHEMBL28438637 | 0.69 | KDM4E (0.43) | KDM4ELMNA | |
| SCHEMBL7834603 | 0.67 | APEX1 (0.71) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |