Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.58 |
| ▸ | MAOA | P21397 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825409 | 0.77 | STS (0.54) | MAOBMAOASTSCA12CA9 | |
| SCHEMBL22916225 | 0.75 | CA12 (0.56) | MAOBMAOACA2STSALDH1A1 | |
| SCHEMBL21213879 | 0.74 | MAOB (1.00) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL4731619 | 0.74 | MAOB (1.00) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL27397632 | 0.73 | STS (0.60) | CA2CA5ASTS | |
| SCHEMBL28445528 | 0.73 | STS (0.60) | CA2CA5ASTSALDH1A1HPGD | |
| SCHEMBL29634256 | 0.73 | STS (0.60) | CA2CA5ASTSALDH1A1HPGD | |
| SCHEMBL14515202 | 0.73 | STS (0.53) | MAOBMAOACA2CA5ASTS | |
| SCHEMBL21365816 | 0.73 | STS (0.50) | STSNPC1RAB9AALOX5 | |
| SCHEMBL29749495 | 0.73 | MAOB (0.57) | MAOBMAOACA2CA5ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129906-A1 | Phenoxyalkoxy-3,4-dihydro-2H-1-benzopyran derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-01-02 | — | — | EP | disclosed |