Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010359 | 1.00 | MGLL (0.58) | MGLLPLK1THRBHTR2AHTR2C | |
| SCHEMBL28675479 | 0.91 | MGLL (0.54) | MGLLPLK1THRBHTR2AHTR2C | |
| SCHEMBL6622933 | 0.89 | MEN1 (0.62) | MGLLPLK1THRBHTR2AHTR2C | |
| SCHEMBL3678830 | 0.85 | MGLL (0.56) | MGLLPLK1HTR2AHTR2CHTR7 | |
| SCHEMBL27458452 | 0.81 | HTR2A (0.51) | MGLLHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL19754954 | 0.80 | KMT2A (0.53) | MGLLHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL13084751 | 0.78 | NPC1 (0.49) | MGLLHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL2763482 | 0.77 | HTR2A (0.48) | HTR2AHTR2CHTR7HTR6NPC1 | |
| SCHEMBL28975172 | 0.77 | HTR2A (0.45) | MGLLHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL3676771 | 0.77 | CES2 (0.50) | HTR2AHTR2CHTR7HTR6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131837-A1 | Liquid crystalline compounds | MERCK PATENT GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |