Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763119 | 0.83 | KMT2A (0.56) | NPC1RAB9AKMT2AHTR2AHTR2C | |
| SCHEMBL3681499 | 0.81 | CA2 (0.52) | NPC1RAB9AKMT2AMEN1CYP2D6 | |
| SCHEMBL3678830 | 0.81 | MGLL (0.56) | NPC1RAB9AKMT2AMEN1CYP2D6 | |
| SCHEMBL27567003 | 0.81 | GAA (0.53) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL19754954 | 0.80 | KMT2A (0.53) | NPC1RAB9AKMT2AMEN1CYP2D6 | |
| SCHEMBL6801531 | 0.78 | LMNA (0.49) | NPC1RAB9AKMT2AMEN1CYP2D6 | |
| SCHEMBL11010367 | 0.78 | MGLL (0.58) | NPC1RAB9AKMT2AHTR2AHTR2C | |
| SCHEMBL11010359 | 0.78 | MGLL (0.58) | NPC1RAB9AKMT2AHTR2AHTR2C | |
| Methane SCHEMBL6326355 | 0.77 | LMNA (0.48) | NPC1RAB9AKMT2AMEN1CYP2D6 | |
| SCHEMBL7498931 | 0.77 | HDAC3 (0.50) | NPC1RAB9AKMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091938-B1 | ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF | AVENTISUB II INC (US) | 2010-10-20 | — | — | EP | disclosed |