Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010515 | 1.00 | GBA1 (0.50) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL7513470 | 0.89 | GBA1 (0.50) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL9346730 | 0.89 | GBA1 (0.50) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL9346744 | 0.89 | GBA1 (0.50) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL11010477 | 0.84 | MAOA (0.43) | KCNH2CCR3PRMT6HRH3ALDH1A1 | |
| SCHEMBL11010385 | 0.84 | GBA1 (0.44) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL11010472 | 0.84 | MAOA (0.43) | KCNH2CCR3PRMT6HRH3ALDH1A1 | |
| SCHEMBL11010383 | 0.84 | GBA1 (0.44) | GBA1KCNH2CCR3PRMT6HRH3 | |
| SCHEMBL11010469 | 0.84 | MAOA (0.43) | KCNH2CCR3PRMT6HRH3ALDH1A1 | |
| SCHEMBL10902242 | 0.84 | KCNH2 (0.58) | GBA1KCNH2CCR3PRMT6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131837-A1 | Liquid crystalline compounds | MERCK PATENT GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |