Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24106016 | 0.88 | LMNA (0.63) | TP53MAPTLMNATHRBPOLB | |
| SCHEMBL11009487 | 0.87 | TP53 (0.56) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL24105991 | 0.86 | TP53 (0.67) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL24106012 | 0.85 | THRB (0.70) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL11011244 | 0.82 | TP53 (0.67) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL24106080 | 0.80 | LMNA (0.62) | TP53MAPTLMNASMN1; SMN2THRB | |
| SCHEMBL11011184 | 0.80 | TP53 (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL11013461 | 0.79 | FLT3 (0.57) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL10803806 | 0.79 | TP53 (0.70) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL24105990 | 0.79 | LMNA (0.68) | TP53MAPTLMNATHRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |