Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584125 | 1.00 | OPRK1 (0.38) | OPRK1OPRM1FURINPCSK6NMT2 | |
| SCHEMBL11011274 | 1.00 | OPRK1 (0.38) | OPRK1OPRM1FURINPCSK6NMT2 | |
| SCHEMBL2183030 | 0.90 | NMT2 (0.38) | OPRK1OPRM1FURINPCSK6NMT2 | |
| SCHEMBL27584151 | 0.90 | NMT2 (0.38) | OPRK1OPRM1FURINPCSK6NMT2 | |
| SCHEMBL28761909 | 0.86 | NPY4R (0.43) | OPRK1FURINPCSK6NMT2NMT1 | |
| SCHEMBL2191184 | 0.84 | DPP8 (0.43) | OPRK1FURINPCSK6NMT2NMT1 | |
| SCHEMBL2183569 | 0.84 | DPP8 (0.43) | OPRK1FURINPCSK6NMT2NMT1 | |
| SCHEMBL2196706 | 0.84 | DPP8 (0.43) | OPRK1FURINPCSK6NMT2NMT1 | |
| SCHEMBL1711321 | 0.83 | CPB2 (0.47) | OPRK1OPRM1FURINPCSK6CPB2 | |
| SCHEMBL1711325 | 0.83 | CPB2 (0.47) | OPRK1OPRM1FURINPCSK6CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505852-A | 7-Amino-4-trifluoromethylquinolone derived substrates and method for determining enzymes and inhibitors | ENZYME SYSTEMS PRODUCTS (US) | 1985-03-19 | — | — | US | claimed |
| US-4505852-A | 7-Amino-4-trifluoromethylquinolone derived substrates and method for determining enzymes and inhibitors | ENZYME SYSTEMS PRODUCTS (US) | 1985-03-19 | — | — | US | disclosed |