Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 7/20 | 0.77 |
| ▸ | MAOA | P21397 | 5/20 | 0.77 |
| ▸ | MAOB | P27338 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | NPC1 | O15118 | 8/20 | 0.76 |
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 8/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.76 |
| ▸ | STAT1 | P42224 | 1/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622990 | 0.90 | ALDH2 (0.78) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1701110 | 0.87 | ALDH2 (1.00) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| Ipriflavone SCHEMBL29485035 | 0.87 | ALDH1A1 (1.00) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| Ipriflavone SCHEMBL111472 | 0.87 | ALDH1A1 (1.00) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10711072 | 0.86 | ALDH2 (0.80) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30527919 | 0.82 | KDM4E (0.81) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL2069094 | 0.82 | KDM4E (0.81) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11012372 | 0.82 | MAPT (0.73) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL738941 | 0.81 | ALDH2 (0.80) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL2069266 | 0.80 | MAPT (0.84) | ALDH2MAOAMAOBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136569-A2 | Isoflavone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | disclosed |