Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 16/20 | 1.00 |
| ▸ | MAOA | P21397 | 7/20 | 1.00 |
| ▸ | MAOB | P27338 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | STAT1 | P42224 | 1/20 | 0.77 |
| ▸ | CASP3 | P42574 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622365 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL738941 | 0.89 | ALDH2 (0.80) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL10338453 | 0.88 | KDM4E (0.80) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| Ipriflavone SCHEMBL29485035 | 0.87 | ALDH1A1 (1.00) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| Ipriflavone SCHEMBL111472 | 0.87 | ALDH1A1 (1.00) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL11012140 | 0.87 | ALDH2 (0.77) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| Isoformonentin SCHEMBL30105310 | 0.86 | XDH (1.00) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| Isoformonentin SCHEMBL73338 | 0.86 | XDH (1.00) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL10796649 | 0.85 | ALDH2 (1.00) | ALDH2MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL1701136 | 0.84 | ALDH2 (0.78) | ALDH2MAOAMAOBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981530-B1 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2020-02-12 | — | — | EP | claimed |
| US-9669004-B2 | Daidzein analogs as treatment for cancer | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2017-06-06 | — | — | US | claimed |
| US-20160068542-A1 | Enhanced Osteogenic Activity of Daidzein Analogs on Human Mesenchymal Stem Cells | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2016-03-10 | — | — | US | claimed |
| EP-2981530-A2 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | The Administrators of the Tulane Educational Fund (US) | 2016-02-10 | — | — | EP | claimed |
| US-20150148409-A1 | NOVEL DAIDZEIN ANALOGS AS TREATMENT FOR CANCER | XAVIER UNIVERSITY OF LOUISIANA | 2015-05-28 | — | — | US | claimed |
| US-8962679-B2 | Daidzein analogs as treatment for cancer | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2015-02-24 | — | — | US | claimed |
| WO-2014165723-A2 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2014-10-09 | — | — | WO | claimed |
| US-20130184475-A1 | NOVEL DAIDZEIN ANALOGS AS TREATMENT FOR CANCER | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2013-07-18 | — | — | US | claimed |
| WO-2012006563-A2 | NOVEL DAIDZEIN ANALOGS AS TREATMENT FOR CANCER | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2012-01-12 | — | — | WO | claimed |
| EP-0136569-A2 | Isoflavone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | claimed |
| JP-60054379-A | — | — | None | — | — | JP | disclosed |
| EP-2981530-B1 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2020-02-12 | — | — | EP | disclosed |
| US-9669004-B2 | Daidzein analogs as treatment for cancer | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669004-B2 | Daidzein analogs as treatment for cancer | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160068542-A1 | Enhanced Osteogenic Activity of Daidzein Analogs on Human Mesenchymal Stem Cells | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2016-03-10 | — | — | US | disclosed |
| WO-2000002553-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING BONE DISEASES USING TOCOTRIENOLS | LIPOGENICS, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
| US-4772627-A | AMORPHOUS DRUG AND ADSORBENT, IMPROVED DISSOLUTION AND ADSORPTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0136569-A2 | Isoflavone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | disclosed |
| JP-S6054379-A | NOVEL 4H-1-BENZOPYRAN-4-ONE DERIVATIVE, ITS PREPARATION AND ITS USE | TAKEDA CHEM IND LTD | 1985-03-28 | — | — | JP | disclosed |
| EP-0129893-A2 | Ground mixture | Takeda Chemical Industries, Ltd. (JP) | 1985-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068542-A1 | Enhanced Osteogenic Activity of Daidzein Analogs on Human Mesenchymal Stem Cells | HPGDS, CXCL12, ALPG | ALDH2 1023/4885MAOA 2979/4885MAOB 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.