Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | FBP1 | P09467 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779928 | 0.85 | LMNA (0.74) | PPARALMNATSHRCYP2C9BLM | |
| SCHEMBL21413780 | 0.83 | LMNA (0.67) | PPARALMNATSHRCYP2C9BLM | |
| SCHEMBL21391383 | 0.82 | PPARA (0.78) | PPARALMNATSHRCYP2C9BLM | |
| Ciprofibrate SCHEMBL26870 | 0.82 | PPARA (1.00) | PPARALMNATSHRCYP2C9BLM | |
| Ciprofibrate SCHEMBL8164529 | 0.82 | PPARA (1.00) | PPARALMNATSHRCYP2C9BLM | |
| Clofibrate SCHEMBL3953607 | 0.77 | PPARA (1.00) | PPARALMNATSHRCYP2C9BLM | |
| Clofibrate SCHEMBL2356 | 0.77 | PPARA (1.00) | PPARALMNATSHRCYP2C9BLM | |
| SCHEMBL3903999 | 0.77 | PPARA (0.76) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL11548436 | 0.77 | PPARA (0.76) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL21413779 | 0.76 | LMNA (0.64) | PPARALMNATSHRCYP2C9BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142979-A2 | Improvements in the production of halocyclopropyl-substituted phenoxyalkanoic acids and esters | STERWIN AG. (CH) | 1985-05-29 | — | — | EP | disclosed |