Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | PPARA | Q07869 | 5/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391383 | 0.85 | PPARA (0.78) | LMNAPPARATSHRCYP2C9BLM | |
| Ciprofibrate SCHEMBL8164529 | 0.85 | PPARA (1.00) | LMNAPPARATSHRCYP2C9BLM | |
| Ciprofibrate SCHEMBL26870 | 0.85 | PPARA (1.00) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL11013173 | 0.85 | PPARA (0.69) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL21413780 | 0.84 | LMNA (0.67) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL10733316 | 0.79 | PPARA (0.53) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL21413779 | 0.79 | LMNA (0.64) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL17268548 | 0.78 | LMNA (0.59) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL5315412 | 0.78 | LMNA (0.67) | LMNAPPARATSHRCYP2C9BLM | |
| SCHEMBL15682180 | 0.77 | LMNA (0.55) | LMNAPPARATSHRCYP2C9BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011985-A | Levo-ciprofibrate | STERLING DRUG INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-5011986-A | Dextro-ciprofibrate | STERLING DRUG INC. (US) | 1991-04-30 | — | — | US | disclosed |