Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18329034 | 0.78 | WDR5 (0.40) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL12767916 | 0.77 | HSD17B10 (0.50) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL7201523 | 0.76 | HSD17B10 (0.54) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL9400489 | 0.75 | HSPA5 (0.58) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| Methyl Alcohol SCHEMBL28184301 | 0.75 | HSD17B10 (0.88) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL13253953 | 0.74 | ALDH1A1 (0.38) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL8872103 | 0.74 | HSD17B10 (1.00) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL184648 | 0.74 | HSD17B10 (1.00) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL6410292 | 0.74 | HSPA5 (0.62) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL25065902 | 0.73 | ALDH1A1 (0.36) | HSD17B10ALDH1A1TSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962244-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2013-08-22 | — | — | US | disclosed |
| US-8377639-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2013-02-19 | — | — | US | disclosed |
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-17 | — | — | US | disclosed |
| EP-1742105-A2 | Photothermographic material | Fuji Photo Film Co., Ltd. (JP) | 2007-01-10 | — | — | EP | disclosed |
| EP-0135017-A1 | Process for the stabilisation of poly(phenylene ether) solutions | BASF Aktiengesellschaft (DE) | 1985-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | HSD17B10 4439/4885ALDH1A1 3135/4885TSHR 4273/4885 |
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | HSD17B10 4439/4885ALDH1A1 3135/4885TSHR 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.