Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362697 | 0.76 | HPGD (0.52) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL11013255 | 0.76 | HSD17B10 (0.56) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL4968551 | 0.75 | ALDH1A1 (0.41) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL4968980 | 0.74 | ALDH1A1 (0.39) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL4970133 | 0.74 | ALDH1A1 (0.39) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL184648 | 0.72 | HSD17B10 (1.00) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL8872103 | 0.72 | HSD17B10 (1.00) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL6410292 | 0.72 | HSPA5 (0.62) | HSD17B10ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL4345522 | 0.71 | HPGD (0.50) | HSD17B10ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL27868063 | 0.71 | TSHR (0.44) | HSD17B10ALDH1A1TSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362068-A2 | NOVEL POLYMERISATION CATALYSTS | BP Chemicals Limited (GB) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002050138-A2 | NOVEL POLYMERISATION CATALYSTS | BP CHEMICALS LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |